Leucocyte and thrombocyte responses in dogs experimentally infected with Trypanosoma brucei
DOI:
https://doi.org/10.19182/remvt.9456Keywords
dogs, Trypanosoma brucei, Experimental infection, Anaemia, blood, NigeriaAbstract
Three dogs were subcutaneously infected with Trypanosoma brucei strain ILRAD 1797. Artificial haemolytic anaemia was induced in 2 other dogs by phlebotomy, heat treatment and re-infusion of the blood, while 2 dogs were kept as control animals. The infected animals developed pan-leucopenia and thrombocytopenia, while the dogs with artificial haemolytic anaemia developed leucocytosis and thrombocytosis. These findings suggest that there was a bone marrow depressing factor in the plasma of T. brucei infected dogs especially as it affected leucocyte production.
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© S.O.Omotainse et al., hosted by CIRAD 1995
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