Experimental infection of Red Sokoto goats with Salmonella typhimurium

Abstract

Salmonella typhimurium infection was experimentally induced in goats by administering 2 x 10¹⁰ organisms per os. The disease produced was characterized by pyrexia, diarrhoea and neutrophilia. One goat died from septicaemia. Somatic « 0 » agglutinins were detected 14 days post infection (p.i.). Excretion of organisms in faeces ceased by 6 weeks p.i. Goats which recovered from primary infection were refractory to a secondary challenge with 2 x 10¹¹ organisms. The results indicate that in the absence of signs of ill-health, the detection of neutrophilia and « 0 » agglutinins and isolation of Salmonella organisms from faeces mainly served as evidence of recent infection.